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    Glossary Alpha-smooth muscle actin

    protein involved in smooth muscle contraction and wound healing

    Alpha-smooth muscle actin (α-SMA) is a protein that plays a crucial role in the contraction of smooth muscle cells, which are found in various tissues like blood vessels and the digestive tract. It is also a marker used by scientists to identify myofibroblasts, cells involved in wound healing and tissue repair. Elevated levels of α-SMA can indicate tissue remodeling or fibrosis, which is the thickening and scarring of connective tissue.

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    1. Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus PLoS ONE · 2025 · 1 citations
    2. Alpha Smooth Muscle Actin role in Androgenetic Alopecia Pathogenesis: Benha Journal of Applied Sciences · 2024
    3. Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures PLoS ONE · 2012 · 58 citations
    4. The repairing of full-thickness skin deficiency and its biological mechanism using decellularized human amniotic membrane as the wound dressing Materials Science and Engineering: C · 2017 · 47 citations
    5. A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies Wound Repair and Regeneration · 2014 · 35 citations
    6. Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration Journal of Materials Science: Materials in Medicine · 2018 · 24 citations
    7. Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model European journal of pharmacology · 2015 · 10 citations
    8. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    9. Histological and immunohistochemical studies of excisional wounds in the rat with special reference to the involvement of the hair follicles in the wound healing process Durham e-Theses (Durham University) · 2000 · 4 citations
    10. 4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression Research Square (Research Square) · 2022
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