Dermal Adipose Tissue in Hair Follicle Cycling: Possible Applications in Alopecia

The 2017 study by U Wollina et al. explored the relationship between dermal adipose tissue and hair follicle cycling, with potential implications for alopecia treatment. The research, conducted on rodents, demonstrated a clear connection between hair follicle cycling and adjacent dermal adipose tissue. The study also highlighted the adipocyte-myofibroblast transition, which could play a significant role in the miniaturization of hair follicles, a key pathophysiological step in androgenetic alopecia. The researchers suggested that improving the adipogenic environment of hair follicles could be beneficial in treating alopecia and enhancing surgical hair restoration procedures.