Dermal Adipose Tissue in Hair Follicle Cycling: Possible Applications in Alopecia

    April 2017 in “ PubMed ”
    Uwe Wollina, Naser M Abdel, Ilja L. Kruglikov
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    TLDR Fat cells near hair follicles may affect hair growth and could help treat baldness.
    The 2017 study by U Wollina et al. explored the relationship between dermal adipose tissue and hair follicle cycling, with potential implications for alopecia treatment. The research, conducted on rodents, demonstrated a clear connection between hair follicle cycling and adjacent dermal adipose tissue. The study also highlighted the adipocyte-myofibroblast transition, which could play a significant role in the miniaturization of hair follicles, a key pathophysiological step in androgenetic alopecia. The researchers suggested that improving the adipogenic environment of hair follicles could be beneficial in treating alopecia and enhancing surgical hair restoration procedures.
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