M2 Macrophages Promote Wound-Induced Hair Neogenesis Through the Production of Growth Factors
M2 macrophages wound-induced hair neogenesis WIHN growth factors wnt signaling pathway full-thickness skin excisions CD11b+ CD68+ CD206+ Igf1 Hgf Egf Fgf2 Fgf10 Wnt proteins hair follicles gene expression analysis insulin-like growth factor 1 hepatocyte growth factor epidermal growth factor fibroblast growth factor 2 fibroblast growth factor 10
Studysummary This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.
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