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This study found that patients with androgenetic alopecia exhibit specific miRNA expression profiles, suggesting that abnormal miR-133b expression may inhibit the Wnt/β-catenin pathway and affect hair growth.

This study discusses the potential of miR-200c-3p as a genetic marker and therapeutic tool for alopecia areata, but it highlights the need for additional methodological details and addresses discrepancies with previous findings on miRNA expression in hair-related processes.

This study identified specific miRNAs that are potentially linked to severe active alopecia areata, suggesting they could be targets for future treatment development.

This study found that integrin-linked kinase is crucial for various epidermal functions, including differentiation and barrier formation, and also plays a previously unreported role in melanocyte development and function.

In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.

This study identified 12 new genes associated with the hair follicle and various stages of the hair cycle in mice, which could lead to novel targets for hair growth or depilation therapies.

This study cataloged several long non-coding RNAs and microRNAs in cashmere goat dermal papilla cells, suggesting these non-coding RNAs may play a role in hair follicle stem cell activation and hair growth.

In this study, researchers used mRNA sequencing to identify and categorize over 49,000 contigs in goat skin, revealing significant gene activity related to metabolism, cell cycle, and cell division during hair growth.

This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.

This article is from the ASPS Education Network and does not report any new research findings.

New treatments using stem cells and other methods show promise for promoting hair growth in androgenetic alopecia.

This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.

In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

This study identified specific gene expression profiles during the intestinal regeneration of sea cucumbers, highlighting potential novel genes and advancing the understanding of regenerative biology in echinoderms.

This study found that miR-486 and miR-451 levels were reduced in alopecia areata-affected skin, and delivering their mimics to mice mitigated symptoms by reducing inflammation and immune activity.

This study observed distinct plasma miRNA profiles in alopecia areata, identifying several miRNAs downregulated in both mild and severe forms; machine learning models demonstrated strong predictive accuracy, and kinase inhibitors were suggested as promising therapeutic targets based on pathway analysis.

This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.

This review highlights that microRNAs (miRNAs) play crucial roles in hair follicle development and cycling in cashmere goats, detailing recent advances in understanding their regulatory functions and potential applications in improving cashmere fiber quality and diagnosing hair disorders.

This study found that upregulating miR-325-3p in glioma suppresses tumor cell proliferation, migration, and invasion by inhibiting FOXM1, suggesting its potential as a treatment target for brain cancer.

This study identified seven genes that may serve as biomarkers for diagnosing skin cutaneous melanoma by analyzing the relationship between UV exposure, ferroptosis, and the cancer's pathology.

This study found that hexane extracts of Nostoc verrucosum significantly inhibited melanin synthesis in melanoma cells and demonstrated antioxidant activity, suggesting potential use in developing cosmetic and functional food products.

This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.

This study demonstrates that inhibiting SFRP1 with the antagonist WAY-316606 enhances hair growth in human scalp hair follicles ex vivo by facilitating Wnt signalling.

This review discusses the therapeutic potential of stem cells from postnatal tissues for regenerative medicine, emphasizing their paracrine effects and the pluripotent potential of very small embryonic-like stem cells.

This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.

In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.

This study found that long non-coding RNAs are differentially expressed in androgenetic alopecia, suggesting potential roles in its development and novel targets for prevention and treatment.

This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.

This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.