Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone

    March 2012 in “ Molecular Medicine Reports ”
    Myung J. Lee, Hwa Jun, Kyung Mi Lim … Sungkwan An
    Studysummary This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.
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    Research cited in this study 12

    1. Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing Seminars in Cutaneous Medicine and Surgery · 2012
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    4. Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2009
    5. The Effect of 5-Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008
    6. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007
    7. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006
    8. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
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