Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells

    January 2016 in “ Annals of Dermatology ”
    Shanghun Shin, Karam Kim, Myung J. Lee … Hwa Jun
    Studysummary This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.
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    Research cited in this study 15

    1. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    2. Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells Molecular Medicine Reports · 2014
    3. Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia Expert Opinion on Therapeutic Targets · 2014
    4. Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells Molecular Medicine Reports · 2014
    5. Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles Journal of Dermatological Science · 2013
    6. The Role of Androgen and Androgen Receptor in Skin-Related Disorders Archives of Dermatological Research · 2012
    7. Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone Molecular Medicine Reports · 2012
    8. Characteristics of Androgenetic Alopecia in Asian Populations Annals of Dermatology · 2012
    9. Differential Expression Analysis of Balding and Nonbalding Dermal Papilla MicroRNAs in Male Pattern Baldness Using a MicroRNA Amplification Profiling Method British Journal of Dermatology · 2011
    10. Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG) Phytomedicine · 2006
    11. Pathogenesis of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2004
    12. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    13. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    14. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    15. Role of 5α-Reductase in Health and Disease Baillière's clinical endocrinology and metabolism · 1994

    Related research 2

    1. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    2. Effects of Testosterone, Dihydrotestosterone, and Estradiol on Growth of Human Hair Outer Root Sheath Keratinocytes In Vitro Archives of Dermatological Research · 1991