Glycome Profiling by Lectin Microarray Reveals Dynamic Glycan Alterations During Epidermal Stem Cell Aging
July 2020
in “
Aging Cell
”
epidermal stem cells aging lectin microarray glycan alterations high mannose-type N-glycans α2-3/6 sialylated complex-type N-glycans sialyltransferase St3gal2 St6gal1 mannosidase Man1a primary keratinocytes cell proliferation regenerative therapy skin aging diagnosis skin stem cells skin aging glycan changes sialylated glycans mannose-type glycans sialyltransferase enzymes mannosidase enzymes keratinocytes cell growth skin regeneration skin aging detection
Studysummary In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.
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