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    Did you mean miR-21?
    Glossary miR-21

    small RNA molecule regulating gene expression and hair follicle development

    miR-21 is a type of microRNA, which are small molecules that help regulate gene expression in cells. It is known to play a role in various biological processes, including cell growth, apoptosis (programmed cell death), and differentiation. In the context of hair and alopecia, miR-21 has been implicated in the regulation of hair follicle development and cycling, and its dysregulation may contribute to hair loss conditions.

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    1. Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling Science Advances · 2020 · 65 citations
    2. miR‐218‐5p regulates skin and hair follicle development through Wnt/β‐catenin signaling pathway by targeting SFRP2 Journal of cellular physiology · 2019 · 54 citations
    3. A lipid–polymer hybrid nanoparticle (LPN)-loaded dissolving microneedle patch for promoting hair regrowth by transdermal miR-218 delivery Biomaterials Science · 2022 · 13 citations
    4. Exosomal miRNA-218–5p derived from low-passage dermal papilla cells modulates hair follicle growth and development Non-coding RNA Research · 2026
    5. 1362 Dermal papilla cell-derived extracellular vesicles as the future tools for hair regeneration 2023
    6. Transgenic Immortalization of Human Dermal Fibroblasts Mediated Through the MicroRNA/SIRT1 Pathway In Vivo · 2021 · 7 citations
    7. LncRNA-PCAT1 maintains characteristics of dermal papilla cells and promotes hair follicle regeneration by regulating miR-329/Wnt10b axis Experimental Cell Research · 2020 · 13 citations
    8. miR-133a-3p and miR-145-5p co-promote goat hair follicle stem cell differentiation by regulating NANOG and SOX9 expression Animal Bioscience · 2023
    9. Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p 2025
    10. miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4 Cells · 2025 · 4 citations
    11. miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network Frontiers in Cell and Developmental Biology · 2022
    12. Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100 Journal of nanobiotechnology · 2021 · 29 citations
    13. MicroRNA in skin diseases European Journal of Dermatology · 2017 · 27 citations
    14. miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020 · 18 citations
    15. miR-129-5p Participates in Hair Follicle Growth by Targeting HOXC13 in Rabbit Genes · 2022 · 5 citations
    16. MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development Cells · 2024 · 4 citations
    17. Mir-574-3p and Mir-125a-5p in Adipose Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/Smad2 Signaling Pathway for the Treatment of Androgenic Alopecia Journal of Investigative Dermatology · 2025
    18. Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis International Journal of Biological Macromolecules · 2025
    19. Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits Animal Bioscience · 2024
    20. CircERCC6 Positively Regulates the Induced Activation of SHF Stem Cells in Cashmere Goats via the miR-412-3p/BNC2 Axis in an m6A-Dependent Manner Animals · 2024
    21. The Enticing Path of miR Therapeutics: Difficult but Not without Prospects Cells · 2022
    22. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    23. Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit (Oryctolagus cuniculus) Hair Follicle Cycle by RNA Sequencing Frontiers in genetics · 2019 · 35 citations
    24. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    25. miR-150 regulates endothelial progenitor cell differentiation via Akt and promotes thrombus resolution Stem Cell Research & Therapy · 2020 · 20 citations
    26. The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat Scientific Reports · 2018 · 13 citations
    27. Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its Target Igf1r in the Adult Rat Ovary International Journal of Molecular Sciences · 2022 · 9 citations
    28. Assessment of miR-19b-3p, miR-182-5p, and miR-155-5p expression and its relationship with alopecia areata severity Archives of Dermatological Research · 2025
    29. Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats International journal of molecular sciences · 2022 · 7 citations
    30. Secreted Frizzled‐Related Protein 2 ( SFRP2 ) Induces Follistatin‐Like 1 ( FSTL1 ) to Regulate Dihydrotestosterone ( DHT )‐Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence Aging Cell · 2026