Neural Progenitor Cell-Derived Nanovesicles Promote Hair Follicle Growth via miR-100
August 2020
in “
Research Square (Research Square)
”
TLDR Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.
The study demonstrated that neural progenitor cell-derived nanovesicles (ReN-NV) promoted hair follicle growth by enhancing dermal papilla cell proliferation and accelerating hair follicle cycling in a mouse model. The mechanism involved the activation of the Wnt/β-catenin signaling pathway, with miR-100 playing a crucial role in this process. These findings suggested that ReN-NV could serve as an effective alternative to extracellular vesicles for hair growth therapy.