MiR-133a-3p and MiR-145-5p Co-Promote Goat Hair Follicle Stem Cell Differentiation by Regulating NANOG and SOX9 Expression

    November 2023 in “ Animal Bioscience ”
    Jian Wang, Xi Wang, Liuming Zhang … Yong Jun Li
    Studysummary This study found that miR-133a-3p and miR-145-5p influenced goat hair follicle stem cell differentiation by inhibiting NANOG expression and promoting SOX9 expression.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on animbiosci.org →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Roles of miRNAs in Sheep Hair Follicle Development BMC genomics · 2022
    2. CircRNA-0100 Positively Regulates the Differentiation of Cashmere Goat SHF-SCs into Hair Follicle Lineage via Sequestering miR-153-3p to Heighten the KLF5 Expression Archives animal breeding/Archiv für Tierzucht · 2022
    3. The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis Frontiers in cell and developmental biology · 2022
    4. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    5. CircRNA-1926 Promotes Differentiation of Goat SHF Stem Cells into Hair Follicle Lineage by miR-148a/b-3p/CDK19 Axis Animals · 2020
    6. Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats Frontiers in Genetics · 2020
    7. MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2 Journal of cellular physiology · 2019
    8. Hair Follicle Stem Cells Isolated from Newborn Yangtze River Delta White Goats Gene · 2019
    9. A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle Journal of Molecular Cell Biology · 2018
    10. LncRNA PlncRNA-1 Regulates Proliferation and Differentiation of Hair Follicle Stem Cells Through TGF-β1-Mediated Wnt/β-Catenin Signal Pathway Molecular Medicine Reports · 2017
    11. A Screen for Key Genes and Pathways Involved in High-Quality Brush Hair in the Yangtze River Delta White Goat PloS one · 2017
    12. Recent Advances in the Epidermal Growth Factor Receptor/Ligand System Biology on Skin Homeostasis and Keratinocyte Stem Cell Regulation Journal of Dermatological Science · 2013
    13. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    14. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    15. Multipotent Hair Follicle Stem Cells Promote Repair of Spinal Cord Injury and Recovery of Walking Function Cell Cycle · 2008