Hair Follicle Stem Cells Isolated from Newborn Yangtze River Delta White Goats

February 2019 in “ Gene ”

Qiang Wang, Jingwen Qu, Yong Jun Li, Dejun Ji, Hao Zhang, Yin X, Jian Wang, Haoyuan Niu

hair follicle stem cells HFSCs CD49f fluorescence activated flow cytometry in vivo grafting models in vitro model multipotency quiescence activation stem cells flow cytometry

Studysummary This study describes two methods for isolating hair follicle stem cells from newborn Yangtze River Delta White Goats, highlighting differences in cell viability and marker protein expression between the methods. Our plain-language summary of this paper — not a Tressless recommendation.

Researchers described two methods for isolating hair follicle stem cells (HFSCs) from newborn Yangtze River Delta White Goats. They found a suitable method and noted differences in cell viability and HFSC marker protein expression between the methods. CD49f-positive HFSCs were sorted using fluorescence activated flow cytometry. These sorted HFSCs could be used in in vivo grafting models and as an in vitro model to study multipotency, quiescence, and activation.

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