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Glossary In Vitro Models

experimental systems studying biological processes outside living organisms

In Vitro Models refer to experimental systems used to study biological processes outside of a living organism, typically in a controlled laboratory environment. These models often involve the use of cell cultures or tissue samples to investigate cellular behaviors, drug responses, or disease mechanisms, providing valuable insights without the ethical and practical complexities of in vivo (within a living organism) studies.

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Research

5 / 1000+ results

research Human hair growth in vitro: a model for the study of hair follicle biology

133 citations , July 1994 in “Journal of Dermatological Science”

In this study, the researchers developed an in vitro model that maintains human hair follicles to grow at in vivo rates and observed that factors like EGF and IGF-I influence hair follicle growth and catagen entry.

Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth

research Review of Hair Follicle Dermal Papilla cells as in vitro</i> screening model for hair growth

76 citations , August 2018 in “International Journal of Cosmetic Science”

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

An In Vitro Model for the Study of Human Hair Growth

research An in Vitro</i> Model for the Study of Human Hair Growth

13 citations , December 1991 in “Annals of the New York Academy of Sciences”

This study observed that human anagen hair follicles can grow in vitro when maintained serum-free, with possible implications for understanding hair follicle growth mechanisms.

research In vitro models to study hair follicle generation

5 citations , November 2017 in “Elsevier eBooks”

This review highlights recent advances in hair follicle research, noting that new 3D culture techniques have enabled formation of HF-like structures in vitro, offering potential benefits for alopecia and burn patients, but it reports no new clinical results.

research In vitro hair follicle growth model for drug testing

3 citations , March 2023 in “Scientific Reports”

This study found that organoid cultures of human epithelial and mesenchymal cells can produce hair peg-like structures, and their growth is enhanced by minoxidil, suggesting potential for hair drug screening.

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Community Join

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community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 1 month ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

community Study on Sugar Intake on Male Pattern Hair Loss

19 upvotes 3 years ago

Excessive sugar and high-fat diets are linked to male pattern hair loss, with sweet beverages being a significant factor. Moderation in diet is advised, as diet alone may not fully prevent hair loss due to other factors like DHT sensitivity.

community Could coffee contribute to hair loss?

4 upvotes 4 years ago

Coffee may negatively impact hair health due to its vasoconstrictor effects, potential to increase DHT, and interference with nutrient absorption. There is no strong clinical evidence linking caffeine to hair loss or regrowth in humans, but moderation is advised.

community IGF-1 and Peptides? Miracle molecule waiting to be found

10 upvotes 1 year ago

The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

community Creatine is the opposite of minoxidil !

324 upvotes 10 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

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