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GlossarymiR-214

regulates gene expression affecting hair follicle development

miR-214 is a type of microRNA, which are small molecules that help regulate gene expression in cells. Specifically, miR-214 has been found to play roles in various biological processes, including cell growth, differentiation, and apoptosis (programmed cell death). In the context of hair and alopecia, miR-214 can influence hair follicle development and cycling, potentially impacting hair growth and loss.

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research Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation Through the Chi-miR-214-3p/Beta-Catenin Axis in Cashmere Goats

7 citations, September 2022 in “International journal of molecular sciences”

The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.

research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway

103 citations, November 2014 in “Journal of Cell Biology”

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages

8 citations, October 2020 in “Stem cell research & therapy”

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

research The Enticing Path of miR Therapeutics: Difficult but Not Without Prospects

January 2022 in “Cells”

Developing microRNA-based treatments is hard but has potential.

research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation

12 citations, January 2022 in “Cells”

Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.

research Dysregulated Behavior of Hair Follicle Stem Cells Triggers Alopecia and Provides Potential Therapeutic Targets

3 citations, May 2022 in “Experimental Dermatology”

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

research Orchestrated Role of MicroRNAs in Skin Development and Regeneration

January 2018 in “Contributions to management science”

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

Stimulation by Exosomes from Hypoxia-Preconditioned Hair Follicle Mesenchymal Stem Cells Facilitates Mitophagy by Inhibiting the PI3K/AKT/mTOR Signaling Pathway to Alleviate Ulcerative Colitis

research Stimulation by Exosomes from Hypoxia-Preconditioned Hair Follicle Mesenchymal Stem Cells Facilitates Mitophagy by Inhibiting the PI3K/AKT/mTOR Signaling Pathway to Alleviate Ulcerative Colitis

January 2024 in “Theranostics”

Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.

research Dermal Papilla Cell-Derived Extracellular Vesicles as the Future Tools for Hair Regeneration

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Dermal papilla cell-derived exosomes can help stem cells grow hair.

research MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2

54 citations, April 2019 in “Journal of cellular physiology”

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

research MiR-92a-1-5p and miR-328-3p Are Up-Regulated in Skin of Female Pattern Hair Loss Patients

4 citations, January 2019 in “Annals of Dermatology”

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

research miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation

19 citations, January 2018 in “BioMed Research International”

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

research MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

18 citations, December 2020 in “Frontiers in cell and developmental biology”

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

research LncRNA-XIST Promotes Dermal Papilla Induced Hair Follicle Regeneration by Targeting miR-424 to Activate Hedgehog Signaling

11 citations, March 2020 in “Cellular Signalling”

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

research N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

2 citations, November 2022 in “Animal Bioscience”

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

research MiR-133a-3p and MiR-145-5p Co-Promote Goat Hair Follicle Stem Cell Differentiation by Regulating NANOG and SOX9 Expression

November 2023 in “Animal Bioscience”

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

research MiR-23b and MiR-133 Cotarget TGFβ2/NOTCH1 in Dermal Fibroblasts and Affect Hair Follicle Development in Sheep

August 2023 in “Research Square (Research Square)”

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

research Chi-miR-30b-5p Inhibits Dermal Papilla Cells Proliferation by Targeting CaMKIIδ Gene in Cashmere Goat

13 citations, June 2020 in “BMC genomics”

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

research CircERCC6 Positively Regulates the Induced Activation of SHF Stem Cells in Cashmere Goats via the miR-412-3p/BNC2 Axis in an m6A-Dependent Manner

January 2024 in “Animals”

Circular RNA ERCC6 helps activate stem cells important for cashmere goat hair growth by interacting with specific molecules in an m6A modification-dependent way.

research MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation

2 citations, February 2022 in “Human Gene Therapy”

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.

research Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle

149 citations, June 2010 in “The FASEB journal”

miR-31 regulates hair growth by controlling gene expression in hair follicles.

research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations, January 2019 in “International journal of biological sciences”

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

research Detection of Hair MicroRNAs as Novel Potent Biomarkers: Evaluation of Usefulness for Scleroderma Diagnosis

39 citations, July 2013 in “Journal of dermatological science”

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration

31 citations, July 2017 in “Clinical Science”

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development

July 2022 in “Research Square (Research Square)”

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

research MicroRNA-148a Controls Epidermal and Hair Follicle Stem/Progenitor Cells by Modulating the Activities of ROCK1 and ELF5

1 citations, September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs as New Molecular Players in Dermatology and Cutaneous Biology

22 citations, April 2017 in “Journal of Investigative Dermatology”

Non-coding RNAs are crucial for skin development and health.

research EZH2-Mediated Inhibition of MicroRNA-22 Promotes Differentiation of Hair Follicle Stem Cells by Elevating STK40 Expression

12 citations, July 2020 in “Aging”

The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

research Retracted Article: Up-Regulated lncRNA5322 Elevates MAPK1 to Enhance Proliferation of Hair Follicle Stem Cells as a ceRNA of microRNA-19b-3p

9 citations, June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

research Implication of MicroRNA Regulation in Para-Phenylenediamine-Induced Cell Death and Senescence in Normal Human Hair Dermal Papilla Cells

8 citations, March 2015 in “Molecular Medicine Reports”

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.