Orchestrated Role of MicroRNAs in Skin Development and Regeneration

The document discussed the critical role of microRNAs (miRNAs) in skin development and regeneration, emphasizing their regulatory functions in processes such as skin stem cell expansion, differentiation, and hair follicle morphogenesis. Specific miRNAs like miR-205 and miR-214 were highlighted for modulating pathways such as PI(3)K and Wnt. The importance of miRNA biogenesis enzymes, such as Dicer and Drosha, in maintaining skin and hair follicle homeostasis was also underscored. Overall, miRNAs were shown to be essential for orchestrating the complex gene expression programs necessary for skin development and regeneration.