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    Glossary Mast Cell Infiltration

    accumulation of immune cells causing inflammation in tissues

    Mast Cell Infiltration refers to the accumulation of mast cells, a type of white blood cell involved in allergic reactions and immune responses, in a specific tissue or organ. This can lead to inflammation and is often associated with conditions like allergies, asthma, and certain types of skin disorders, including some forms of alopecia.

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    1. 863 Central centrifugal cicatricial alopecia gene expression analysis revealed cholesterol, fatty acid, and mast cell pathways 2019
    2. Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis Annals of Translational Medicine · 2022
    3. Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study Galen Medical Journal · 2020
    4. Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury Journal of radiation research · 2017 · 19 citations
    5. Pimecrolimus interferes the therapeutic efficacy of human mesenchymal stem cells in atopic dermatitis by regulating NFAT-COX2 signaling Stem Cell Research & Therapy · 2021 · 11 citations
    6. Dorsal skin responses to subchronic ultraviolet B (UVB)-irradiation in Wistar-derived hypotrichotic WBN/ILA-Ht rats. PubMed · 2002 · 7 citations
    7. Efficacy of Glycyrrhetinic Acid in the Treatment of Acne Vulgaris Based on Network Pharmacology and Experimental Validation Molecules · 2024 · 5 citations
    8. Alopecia Areata Springer eBooks · 2017 · 1 citations
    9. Multi-Omics Reveals That Hydroxypinacolone Retinoate Alleviates UV-Induced Skin Aging via the p38/MMP9/Collagen Axis Clinical Cosmetic and Investigational Dermatology · 2026
    10. 51012 Clinical and pathophysiological study of seborrheic capitis: focus on brain-skin connection Journal of the American Academy of Dermatology · 2024
    11. Primary cicatricial alopecia associated with systemic indolent mastocytosis JAAD case reports · 2020
    12. 915 Dietary grape powder inhibits atopic dermatitis-like skin lesions in NC/Nga mice Journal of Investigative Dermatology · 2019
    13. Early stage alopecia areata is associated with inflammation in the upper dermis and damage to the hair follicle infundibulum Australasian Journal of Dermatology · 2013 · 22 citations
    14. Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection Allergo Journal · 2000 · 7 citations
    15. Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study Galen Medical Journal · 2020
    16. Studies on equine eosinophilic granuloma and mast cell tumour University of Liverpool · 2019
    17. Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases Research Square (Research Square) · 2023
    18. Identification of Immune Microenvironment Changes, Immune-Related Pathways and Genes in Male Androgenetic Alopecia Research Square (Research Square) · 2023
    19. Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study International Journal of Dermatology · 2023
    20. Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells Nutrients · 2019 · 20 citations
    21. A case of systemic mastocytosis - an ultrastructural and immunohistochemical study of the dermal mast cells in relation to activation of the epidermal melanin unit Journal of The European Academy of Dermatology and Venereology · 1998 · 2 citations
    22. Mast-cell driven dermal white adipose tissue remodeling amplifies inflammation and fibrosis in atopic dermatitis 2026
    23. Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition Journal of Molecular Medicine · 2005 · 76 citations
    24. The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus Veterinary Dermatology · 1990 · 18 citations
    25. Immune cell regulation of the hair cycle Experimental Dermatology · 2020 · 27 citations
    26. Presence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium International Journal of Trichology · 2017 · 9 citations
    27. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    28. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    29. Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation Scientific Reports · 2017 · 27 citations
    30. 269 Down-regulatory role of cholecystokinin on psoriatic epidermal inflammation Journal of Investigative Dermatology · 2017