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    Glossary Mast Cell Degranulation

    cells release histamine and other chemicals causing inflammation

    Mast Cell Degranulation, also known as Mast Cell Activation, is a process where mast cells release granules containing histamine, cytokines, and other inflammatory mediators into the surrounding tissue. This release can trigger allergic reactions, inflammation, and other immune responses, playing a crucial role in conditions like asthma, eczema, and anaphylaxis.

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    1. Presence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium International Journal of Trichology · 2017 · 9 citations
    2. Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle The Journal of Allergy and Clinical Immunology · 2018 · 8 citations
    3. Sorafenib stimulates human skin type mast cell degranulation and maturation Journal of dermatological science · 2017 · 7 citations
    4. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    5. The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus Veterinary Dermatology · 1990 · 18 citations
    6. Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints Stem Cell Research & Therapy · 2021 · 8 citations
    7. 509 Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosis Journal of Investigative Dermatology · 2024
    8. Probing the Effects of Stress Mediators on the Human Hair Follicle American Journal of Pathology · 2007 · 159 citations
    9. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    10. Antianaphylactic activity of alcoholic extract of<i>Eclipta alba</i> Journal of Young Pharmacists · 2009 · 19 citations
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