Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium

January 2017 in “ International Journal of Trichology ”

Shane Grace, Angela Sutton, Nina F. Abraham, Eric S. Armbrecht, Claudia I. Vidal

mast cells mast cell degranulation telogen effluvium Alopecia areata Androgenic alopecia scalp biopsies stress-induced hair loss

TLDR The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.

The 2016 study "Presence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium" investigated the role of mast cells in telogen effluvium, a common hair loss condition. The researchers conducted scalp biopsies on 10 patients with telogen effluvium, 7 with Alopecia areata, and 9 with Androgenic alopecia. They found a significantly higher mean mast cell count in telogen effluvium patients compared to the other groups, suggesting that mast cells could play a role in stress-induced hair loss. The study proposed that modulating mast cell activity could be a promising therapeutic approach for these patients, and called for clinical trials to further investigate this potential treatment.

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research Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium

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The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.