A Retrospective Study of Thyroid Structural Abnormalities in Alopecia Patients

In a retrospective study from 2011, researchers found that 20.2% of 367 alopecia patients had thyroid abnormalities not detected by serum thyroid function tests. Of the 52 patients who underwent an ultrasound after abnormal manual examination findings, 78.8% had abnormal ultrasound results, with 78% of these showing normal thyroid function tests. The study included various types of non-scarring alopecia but did not link any specific thyroid abnormality to a particular type of hair loss. The study concluded that manual thyroid examinations could reveal additional abnormalities in alopecia patients and highlighted the need for further research due to limitations such as its retrospective nature, small sample size, and high attrition rate for ultrasound follow-up. The relationship between thyroid abnormalities and alopecia remains unclear, and future studies are needed to assess the risk of malignant transformation in these patients.