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    Glossary Mast Cell Degranulation

    cells release histamine and other chemicals causing inflammation

    Mast Cell Degranulation, also known as Mast Cell Activation, is a process where mast cells release granules containing histamine, cytokines, and other inflammatory mediators into the surrounding tissue. This release can trigger allergic reactions, inflammation, and other immune responses, playing a crucial role in conditions like asthma, eczema, and anaphylaxis.

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    1. Presence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium International Journal of Trichology · 2017 · 9 citations
    2. Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle The Journal of Allergy and Clinical Immunology · 2018 · 8 citations
    3. Sorafenib stimulates human skin type mast cell degranulation and maturation Journal of dermatological science · 2017 · 7 citations
    4. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    5. The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus Veterinary Dermatology · 1990 · 18 citations
    6. Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints Stem Cell Research & Therapy · 2021 · 8 citations
    7. 509 Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosis Journal of Investigative Dermatology · 2024
    8. Probing the Effects of Stress Mediators on the Human Hair Follicle American Journal of Pathology · 2007 · 159 citations
    9. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    10. Antianaphylactic activity of alcoholic extract of<i>Eclipta alba</i> Journal of Young Pharmacists · 2009 · 19 citations
    11. Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo 2017 · 13 citations
    12. Inhibitory effect of tianeptine on catagen induction in alopecia areata-like lesions induced by ultrasonic wave stress in mice Clinical and Experimental Dermatology · 2013 · 7 citations
    13. Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection Allergo Journal · 2000 · 7 citations
    14. Dermographic urticaria induced by long-pulsed diode laser-assisted epilation: Rare etiology of a common eruption Indian Dermatology Online Journal · 2017 · 2 citations
    15. Effect of Nymphaea caerulea Flower Extract on Improving Scalp Diseases Korean Journal of Pharmacognosy · 2024
    16. 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment Journal of Investigative Dermatology · 2019
    17. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009 · 53 citations
    18. Calcitonin gene‐related peptide (CGRP) may award relative protection from interferon‐γ‐induced collapse of human hair follicle immune privilege Experimental Dermatology · 2011 · 47 citations
    19. Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation Cancer Research · 2012
    20. Novel lysophosphoplipid receptors: their structure and function Journal of Lipid Research · 2014 · 158 citations
    21. Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases Elsevier eBooks · 2012 · 4 citations
    22. Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition Journal of Molecular Medicine · 2005 · 76 citations
    23. Mast-cell driven dermal white adipose tissue remodeling amplifies inflammation and fibrosis in atopic dermatitis 2026
    24. Immune cell regulation of the hair cycle Experimental Dermatology · 2020 · 27 citations
    25. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    26. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    27. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    28. A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis International Journal of Molecular Sciences · 2020 · 35 citations
    29. Hair Growth-Promoting Effects of Lavender Oil in C57BL/6 Mice Toxicological Research · 2016 · 18 citations
    30. Platycarya strobilacea S. et Z. Extract Has a High Antioxidant Capacity and Exhibits Hair Growth-promoting Effects in Male C57BL/6 Mice Journal of Food Science and Nutrition · 2014 · 12 citations