Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study

Male pattern baldness involves genetics, hormones, and needs better treatments.

The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.

Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.

Alopecia areata causes significant emotional distress, including high rates of depression and anxiety.