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    Glossary Perifollicular

    area surrounding hair follicle

    Perifollicular refers to the area surrounding a hair follicle. In medical and dermatological contexts, this term is often used to describe conditions or observations, such as inflammation or fibrosis, that occur around the hair follicles. For example, perifollicular inflammation is a common feature in certain types of hair loss, like alopecia areata, where the immune system attacks the hair follicles.

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    1. Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003 · 194 citations
    2. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006 · 44 citations
    3. Perifollicular erythema as a trichoscopy sign of progression in frontal fibrosing alopecia International journal of trichology · 2013 · 40 citations
    4. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021 · 38 citations
    5. Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration Journal of Investigative Dermatology · 1992 · 33 citations
    6. Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation International Journal of Cosmetic Science · 2016 · 30 citations
    7. Multiple perifollicular fibromas: report of a case and analysis of the literature Journal of Cutaneous Pathology · 1994 · 30 citations
    8. Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts. PubMed · 2012 · 26 citations
    9. Hair growth control by innate immunocytes: Perifollicular macrophages revisited Experimental Dermatology · 2019 · 21 citations
    10. Perifollicular Xanthomas Associated with Epidermal Growth Factor Receptor Inhibitor Therapy Acta Dermato Venereologica · 2010 · 17 citations
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    Community 4

    1. Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA? Reddit · 30 Mar 2022
    2. Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia. Reddit · 20 May 2024
    3. Reducing Fibrosis in Hair Loss: Topical Pirfenidone Reddit · 26 Mar 2026
    4. Testosterone in Reference Range Doesn't Cause Hair Loss Reddit · 2 Feb 2024

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