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    Glossary Perifollicular

    area surrounding hair follicle

    Perifollicular refers to the area surrounding a hair follicle. In medical and dermatological contexts, this term is often used to describe conditions or observations, such as inflammation or fibrosis, that occur around the hair follicles. For example, perifollicular inflammation is a common feature in certain types of hair loss, like alopecia areata, where the immune system attacks the hair follicles.

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    1. Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003 · 194 citations
    2. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006 · 44 citations
    3. Perifollicular erythema as a trichoscopy sign of progression in frontal fibrosing alopecia International journal of trichology · 2013 · 40 citations
    4. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021 · 38 citations
    5. Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration Journal of Investigative Dermatology · 1992 · 33 citations
    6. Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation International Journal of Cosmetic Science · 2016 · 30 citations
    7. Multiple perifollicular fibromas: report of a case and analysis of the literature Journal of Cutaneous Pathology · 1994 · 30 citations
    8. Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts. PubMed · 2012 · 26 citations
    9. Hair growth control by innate immunocytes: Perifollicular macrophages revisited Experimental Dermatology · 2019 · 21 citations
    10. Perifollicular Xanthomas Associated with Epidermal Growth Factor Receptor Inhibitor Therapy Acta Dermato Venereologica · 2010 · 17 citations
    11. Evaluation of perifollicular inflammation of donor area during hair transplantation in androgenetic alopecia and its comparison with controls International Journal of Trichology · 2013 · 13 citations
    12. Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis Journal of Controlled Release · 2022 · 12 citations
    13. Nevus lipomatosus cutaneous superficialis with perifollicular fibrosis. PubMed · 2004 · 12 citations
    14. The induction by topical minoxidil of increased fenestration in the perifollicular capillary wall British Journal of Dermatology · 1999 · 12 citations
    15. Perifollicular haemorrhage with corkscrew hair due to scurvy Postgraduate Medical Journal · 2015 · 9 citations
    16. Hyaluronate Accumulation and Decreased CD44 Expression in Perifollicular Solitary Cutaneous Myxoma Dermatology · 2002 · 9 citations
    17. Subclinical speckled perifollicular melanosis of the scalp. PubMed · 2003 · 7 citations
    18. Aging‐associated perifollicular changes and calcium deposition in poodles Veterinary Dermatology · 2018 · 2 citations
    19. Perifollicular Microscarring in Alopecia Areata and Pattern Hair Loss American Journal of Dermatopathology · 2023 · 1 citations
    20. Perifollicular inflammation and follicular spongiosis in androgenetic alopecia Journal of The American Academy of Dermatology · 2021 · 1 citations
    21. Perifollicular fibrosis and inflammation in androgenetic alopecia and seborrheic dermatitis: diagnostic challenges in differentiation from fibrosing alopecia in a pattern distribution Anais Brasileiros de Dermatologia · 2026
    22. Taurine‐based Active Pharmaceutical Ingredient Ionic Liquids Modulate the Perifollicular Microenvironment for Androgenic Alopecia Treatment Advanced Healthcare Materials · 2026
    23. Perifollicular Fibrosis in Androgenetic Alopecia Brazilian Journal of Hair Health · 2026
    24. Preferential crosstalk between perifollicular capillary vessels and dermal papilla cells during hair cycling homeostasis Scientific Reports · 2026
    25. Perifollicular Elastolysis: A Systematic Review of Clinical Characteristics, Histopathology, and Therapeutic Outcomes Cosmetics · 2026
    26. Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp Clinical Cosmetic and Investigational Dermatology · 2026
    27. Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp DOAJ (DOAJ: Directory of Open Access Journals) · 2026
    28. Preferential Crosstalk between Perifollicular Capillary Vessels and Dermal Papilla Cells during Hair Cycling Homeostasis Research Square (Research Square) · 2025
    29. Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment Journal of Ethnopharmacology · 2024
    30. Perifollicular Melanocyte Regeneration in Bullous Pemphigoid Cureus · 2024