Accelerated Senescence in Skin in a Murine Model of Radiation-Induced Multi-Organ Injury

    February 2017 in “ Journal of radiation research
    Elizabeth A McCart, Rajesh L. Thangapazham, Eric Lombardini, Steven Mog, Ronald Allan M Panganiban, Kelley M Dickson, Rihab A Mansur, Vitaly Nagy, Sung-Yop Kim, Reed Selwyn, Michael R. Landauer, Thomas N. Darling, Regina M. Day
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    Studysummary This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.
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