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Glossary Skin Ulcers

open sores on skin that don't heal properly

Skin ulcers, also known as cutaneous ulcers or dermal ulcers, are open sores on the skin that fail to heal properly and can become chronic. They often result from poor blood circulation, prolonged pressure, or underlying medical conditions such as diabetes or vascular diseases. These ulcers can be painful, prone to infection, and may require medical intervention to promote healing and prevent complications.

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Research

5 / 1000+ results

research Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine

56 citations , March 2016 in “International Wound Journal”

This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.

research Skin microbiota and diabetic foot ulcers

6 citations , July 2025 in “Frontiers in Microbiology”

This study observed that in patients with diabetic foot ulcers, an imbalance in skin microbiota, with increased pathogenic bacteria, contributes to infection and poor wound healing, and suggests that modulating microbiota composition might improve healing outcomes.

research Hair-follicle transplant as chronic skin ulcer treatment

May 2022 in “Portuguese Journal of Dermatology and Venereology”

In this study, a case of chronic skin ulcer due to livedoid vasculopathy fully healed following hair-follicle transplantation, suggesting potential effectiveness of this treatment approach.

research Hair follicle transplantation promotes skin ulcer healing in a mouse model of experimental diabetes

August 2025 in “Scientific Reports”

This study found that hair follicle transplantation improved wound healing in diabetic mice by promoting tissue regeneration and reducing inflammation, with follicles from normoglycemic conditions proving more effective than those from hyperglycemic environments.

research Exercise in dermatology: Exercise’s influence on skin aging, skin cancer, psoriasis, venous ulcers, and androgenetic alopecia

2 citations , August 2021 in “Journal of The American Academy of Dermatology”

In this study, researchers reviewed the literature on the preventive and therapeutic roles of exercise in various skin diseases and assessed whether there are sufficient data to recommend exercise for each condition.

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Community Join

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community Has Anyone used deoxyribose sugar (gel) and seen notable results?

4 upvotes 1 year ago

Deoxyribose sugar gel is discussed as a potential hair loss treatment, but it lacks human trials and credible evidence. Users express skepticism and humor about its effectiveness compared to established treatments like minoxidil and finasteride.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community 10.5 months. Oral propecia, topical minoxidil (once daily) derma roller. And for the last two (2) months, I've been doing the bald showers after leg workouts... Biotin and Omega 3 age 35. Loses a lot of hair a day, over 150

245 upvotes 2 years ago

A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.

community What happened to the big three? Ketoconazole is pretty magic for some and over the last few years it has been missing in people’s regiment quite a bit

in Product 109 upvotes 1 year ago

Ketoconazole, once popular for hair health, is now less mentioned, with mixed reviews on its benefits for scalp health. Microneedling is discussed as a potential alternative to traditional treatments like finasteride and minoxidil, with varied opinions on its effectiveness.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 year ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

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Learn

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learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin