Primary Cicatricial Alopecia Associated With Systemic Indolent Mastocytosis
February 2020
in “
JAAD case reports
”
TLDR Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
A 63-year-old woman with systemic indolent mastocytosis (SM) and telangiectasia macularis eruptiva perstans (TMEP) presented with primary cicatricial alopecia (PCA) affecting her eyebrows, eyelashes, and scalp. Histological analysis of her scalp biopsy revealed significant mast cell infiltration, suggesting a link between mastocytosis and PCA. Treatment with topical tacrolimus led to complete resolution of her scalp symptoms. This case supports the emerging evidence that mast cells may play a crucial role in the pathogenesis of PCA, highlighting the need for further research and consideration of mastocytosis in patients with scarring alopecia.
