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    GlossaryScarring Alopecia (Primary Cicatricial Alopecia)

    inflammation destroys hair follicles, replacing them with scar tissue

    Scarring Alopecia, also known as cicatricial alopecia, is a group of hair loss disorders where inflammation destroys hair follicles and replaces them with scar tissue, leading to permanent hair loss. This condition can be caused by various factors, including autoimmune diseases, infections, or physical trauma, and often requires a biopsy for accurate diagnosis and targeted treatment.

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      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

      learn Castor oil

      a traditional, natural remedy touted for promoting scalp health and hair growth

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

    Research

    5 / 1000+ results
      The Pathogenesis of Primary Cicatricial Alopecias

      research The Pathogenesis of Primary Cicatricial Alopecias

      150 citations, November 2010 in “The American Journal of Pathology”
      The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
      Primary Cicatricial Alopecia

      research Primary Cicatricial Alopecia

      65 citations, December 2016 in “Journal of The American Academy of Dermatology”
      The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.
      Primary Cicatricial Alopecia: Diagnosis and Treatment

      research Primary Cicatricial Alopecia: Diagnosis and Treatment

      48 citations, May 2013 in “Canadian Medical Association Journal”
      Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

    Community Join

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  692 upvotes 1 month ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 4 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community We need to keep these snake oil companies accountable.

      in Treatment  119 upvotes 2 months ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.