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    GlossaryScarring Alopecia (Primary Cicatricial Alopecia)

    inflammation destroys hair follicles, replacing them with scar tissue

    Scarring Alopecia, also known as cicatricial alopecia, is a group of hair loss disorders where inflammation destroys hair follicles and replaces them with scar tissue, leading to permanent hair loss. This condition can be caused by various factors, including autoimmune diseases, infections, or physical trauma, and often requires a biopsy for accurate diagnosis and targeted treatment.

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      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

      learn Castor oil

      a traditional, natural remedy touted for promoting scalp health and hair growth

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

    Research

    5 / 1000+ results
      The Pathogenesis of Primary Cicatricial Alopecias

      research The Pathogenesis of Primary Cicatricial Alopecias

      150 citations, October 2010 in “The American Journal of Pathology”
      The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
      Primary Cicatricial Alopecia

      research Primary Cicatricial Alopecia

      65 citations, November 2016 in “Journal of The American Academy of Dermatology”
      The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

    Community Join

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  55 upvotes 2 weeks ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  96 upvotes 1 month ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.