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    Glossary Hair Differentiation

    process where cells become specialized to form hair

    Hair differentiation refers to the process by which cells in the hair follicle develop into specialized hair cells. This involves a series of genetic and biochemical changes that enable these cells to produce the structural proteins, like keratin, that form the hair shaft. For professionals, understanding hair differentiation is crucial for studying hair growth disorders and developing treatments for conditions like alopecia.

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    1. Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin Physiological Genomics · 2004 · 90 citations
    2. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    3. Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling ˜The œAmerican journal of pathology · 2004 · 65 citations
    4. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    5. Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 -Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation 2015 · 16 citations
    6. EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression Aging · 2020 · 12 citations
    7. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response Scientific Reports · 2017 · 7 citations
    8. The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles Open Life Sciences · 2023
    9. A function for Rac1 in the terminal differentiation and pigmentation of hair Development · 2012
    10. Lack of the Vitamin D Receptor is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth 2002 · 180 citations
    11. The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling ˜The œAmerican journal of pathology · 2002 · 146 citations
    12. Dlx3 is a crucial regulator of hair follicle differentiation and cycling Development · 2008 · 132 citations
    13. Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation Mechanisms of Development · 1999 · 79 citations
    14. Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog Journal of Investigative Dermatology · 2007 · 70 citations
    15. Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family Development · 1992 · 65 citations
    16. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    17. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    18. Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature 2020 · 15 citations
    19. Using High-Throughput Immunoblotting to Identify Proteins Involved in the Differentiation of ES Cells along the Hair Follicle Lineage in Vitro Stem Cell Reviews and Reports · 2011 · 4 citations
    20. 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth 2023
    21. 604 DNA dioxygenases TET regulate keratin gene expression and enhancer networks within lineage-specific gene loci during epidermal and hair follicle-specific keratinocyte differentiation 2021
    22. 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath 2019
    23. The study of improvement of hair follicle stem cells of rats in vitro culture identification and differentiation Chin J Anat Clin · 2016
    24. Claudin tight junctionwhat's your function? The role of Claudin 6 in epidermal and hair follicle differentiation uO Research (University of Ottawa) · 2004
    25. Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours Development · 2002 · 297 citations
    26. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013 · 277 citations
    27. Hair follicle stem cells:<i>In vitro</i>and<i>in vivo</i>neural differentiation World journal of stem cells · 2015 · 25 citations
    28. Lithium chloride promotes the odontoblast differentiation of hair follicle neural crest cells by activating Wnt/β‐catenin signaling Cell Biology International · 2014 · 16 citations
    29. Mechanotransductive Differentiation of Hair Follicle Stem Cells Derived from Aged Eyelid Skin into Corneal Endothelial-Like Cells Stem Cell Reviews and Reports · 2021 · 9 citations
    30. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations