Co-Expression Pattern of VEGFR-2 With Indicators Related to Proliferation, Apoptosis, and Differentiation of Anagen Hair Follicles

    January 2023 in “ Open Life Sciences ”
    Ru Dai, Qi Xu, Zewei Shao, Xianjie Wu
    Studysummary This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.
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    Research cited in this study 16

    1. Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling npj Regenerative Medicine · 2022
    2. Vitamins and Their Derivatives Synergistically Promote Hair Shaft Elongation via PlGF/VEGFR-1 Signalling Activation Journal of dermatological science · 2022
    3. Activation of Camp Signaling in Response to Alpha-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells International journal of molecular sciences · 2022
    4. Insights Into Male Androgenetic Alopecia Using Comparative Transcriptome Profiling: Hypoxia-Inducible Factor-1 and Wnt/Beta-Catenin Signalling Pathways British Journal of Dermatology · 2022
    5. The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis Frontiers in cell and developmental biology · 2021
    6. Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor Archives of Dermatological Research · 2020
    7. Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia Dermatologic Surgery · 2019
    8. VEGFR-2 Is in a State of Activation in Hair Follicles, Sebaceous Glands, Eccrine Sweat Glands, and Epidermis from Human Scalp: An In Situ Immunohistochemistry Study of Phosphorylated VEGFR-2 Medical science monitor basic research/Medical science monitor. Basic research · 2019
    9. Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF Nature Communications · 2017
    10. Paracrine Crosstalk Between Human Hair Follicle Dermal Papilla Cells and Microvascular Endothelial Cells Experimental Dermatology · 2015
    11. VEGF165 Modulates Proliferation, Adhesion, Migration, and Differentiation of Cultured Human Outer Root Sheath Cells from Central Hair Follicle Epithelium Through VEGFR-2 Activation In Vitro Journal of Dermatological Science · 2013
    12. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    13. Androgenetic Alopecia and Current Methods of Treatment PubMed · 2005
    14. The In Vitro Assembly of Hair Follicle Keratins: Comparison of Cortex and Companion Layer Keratins Biological chemistry · 2002
    15. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    16. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000

    Related research 3

    1. Co-Expression Pattern of VEGFR-2 With Indicators Related to Proliferation, Apoptosis, and Differentiation of Anagen Hair Follicles Open Life Sciences · 2023
    2. Epidermis Reconstructed from the Outer Root Sheath of Human Hair Follicle: Effect of Retinoic Acid Archives of Dermatological Research · 1993
    3. Biochemistry of Transglutaminases and Cross-Linking in the Skin Journal of Investigative Dermatology · 1983