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GlossaryLaminin-332 (Laminin 5)

protein crucial for skin's structural integrity and function

Laminin-332, also known as Laminin-5, is a protein crucial for the structural integrity and function of the skin. It is a key component of the basement membrane, which supports the attachment of the epidermis (outer skin layer) to the dermis (inner skin layer). Deficiencies or mutations in Laminin-332 can lead to skin disorders such as junctional epidermolysis bullosa, a condition characterized by fragile skin that blisters easily.

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research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis

102 citations, August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

13 citations, June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia

13 citations, April 2010 in “Journal of dermatological science”

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

research Spatial And Temporal Control Of Laminin-511 And -332 Expressions During Catagen

6 citations, April 2010 in “Journal of Dermatological Science”

Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.

research Laminin-511 Is a New Player in the Development of Psoriasis and Controlled via Cannabinoid Receptor Type 1

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Laminin-511 is involved in psoriasis development and can be regulated by cannabinoid receptor type 1.

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community Summary of Procapil video by Haircafe

in Minoxidil 1 upvotes 1 week ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.