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GlossaryInvolucrin

protein in skin cells aiding barrier formation

Involucrin is a protein found in the upper layers of the skin, specifically in the cells of the epidermis. It plays a crucial role in forming the protective barrier of the skin by contributing to the structure of the cornified envelope, which helps protect against environmental damage and water loss.

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research Regulation of Involucrin Gene Expression

138 citations , June 2004 in “Journal of Investigative Dermatology”

Involucrin gene expression is controlled by specific proteins and signaling pathways.

research Expression of Involucrin in Normal, Hyperproliferative, and Neoplastic Mouse Keratinocytes

58 citations , December 2000 in “Experimental Dermatology”

Involucrin is a useful marker for keratinocyte differentiation in mice.

research Immunohistochemical Localization of Cytokeratins and Involucrin in Calcifying Epithelioma: Comparative Studies with Normal Skin

49 citations , July 2006 in “British Journal of Dermatology”

Calcifying epithelioma cells can differentiate into hair cortex and outer root sheath.

research Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation

23 citations , January 1986

Involucrin is crucial for skin cell maturation and protection.

Ultrastructural Immunolocalization of Involucrin in the Medulla and Inner Root Sheath of Human Hair

research Ultrastructural Immunolocalization of Involucrin in the Medulla and Inner Root Sheath of Human Hair

7 citations , December 2011 in “Annals of anatomy”

Involucrin helps strengthen the inner parts of human hair.

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