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    Glossary Extracellular Vesicles

    tiny, membrane-bound particles released by cells for communication

    Extracellular Vesicles (EVs) are tiny, membrane-bound particles released by cells into the surrounding environment. They play a crucial role in cell-to-cell communication by transporting proteins, lipids, and genetic material between cells, which can influence various biological processes, including immune responses and tissue repair.

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    1. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020 · 220 citations
    2. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    3. Extracellular Vesicles in Skin Wound Healing Pharmaceuticals · 2021 · 106 citations
    4. Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation Stem Cell Research & Therapy · 2020 · 90 citations
    5. Extracellular vesicles as human therapeutics: A scoping review of the literature Journal of Extracellular Vesicles · 2024 · 88 citations
    6. Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies Signal Transduction and Targeted Therapy · 2025 · 77 citations
    7. Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles Stem Cell Research & Therapy · 2020 · 60 citations
    8. Macrophage-Derived Extracellular Vesicle Promotes Hair Growth Cells · 2020 · 51 citations
    9. Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications Molecular Biomedicine · 2024 · 41 citations
    10. The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics International Journal of Molecular Sciences · 2019 · 38 citations
    11. Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin Stem cells · 2019 · 37 citations
    12. Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice Journal of Nanobiotechnology · 2022 · 29 citations
    13. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    14. Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing Stem cell research & therapy · 2022 · 22 citations
    15. Effects of Hydrogels on Mesenchymal Stem/Stromal Cells Paracrine Activity and Extracellular Vesicles Production Journal of Extracellular Vesicles · 2025 · 21 citations
    16. miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020 · 18 citations
    17. Effectiveness of Extracellular Vesicle Application in Skin Aging Treatment and Regeneration: Do We Have Enough Evidence from Clinical Trials? International Journal of Molecular Sciences · 2025 · 16 citations
    18. Methods and Challenges in Purifying Drug‐Loaded Extracellular Vesicles Journal of Extracellular Vesicles · 2025 · 15 citations
    19. Extracellular Vesicles for Regenerative Medicine Applications Applied Sciences · 2022 · 14 citations
    20. Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics Frontiers in cell and developmental biology · 2022 · 13 citations
    21. Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation Cells · 2022 · 12 citations
    22. Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions International Journal of Nanomedicine · 2021 · 10 citations
    23. Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker Stem Cell Research & Therapy · 2025 · 9 citations
    24. The therapeutic, diagnostic, and prognostic values of extracellular vesicles (exosomes) in dermatology: A systematic review JAAD reviews. · 2024 · 9 citations
    25. Extracellular Vesicles in Osteogenesis: A Comprehensive Review of Mechanisms and Therapeutic Potential for Bone Regeneration Current Issues in Molecular Biology · 2025 · 9 citations
    26. Extracellular Vesicles in Facial Aesthetics: A Review International Journal of Molecular Sciences · 2022 · 8 citations
    27. Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury Burns and trauma · 2022 · 8 citations
    28. Quantifying extracellular vesicle heterogeneity: the effect of process conditions on protein cargo for skin therapy Stem Cell Research & Therapy · 2025 · 7 citations
    29. Native and engineered extracellular vesicles for wound healing Frontiers in Bioengineering and Biotechnology · 2022 · 7 citations
    30. Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality Life · 2023 · 7 citations