Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet-Rich Plasma: A Literature Review

    December 2024 in “ Journal of Cosmetic Dermatology
    Aditya K. Gupta, Tong Wang, Jeffrey A. Rapaport, Mesbah Talukder
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    TLDR Exosomes from platelet-rich plasma may help heal wounds but need more research for hair growth and skin use.
    Exosomes derived from platelet-rich plasma show promising therapeutic potential, particularly in wound healing, as evidenced by preclinical studies demonstrating faster wound contraction and enhanced angiogenesis in diabetic animal models. However, there is limited information on their application in hair growth and skin rejuvenation. Current challenges include optimizing isolation techniques, activation methods, and delivery systems. Novel delivery methods, such as hydrogel-based preparations, could facilitate topical application. Further research is necessary to standardize the use of these exosomes in clinical settings.
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