Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet-Rich Plasma: A Literature Review

This literature review examines the therapeutic potential of exosomes derived from platelet-rich plasma (PRP) in dermatology, focusing on wound healing, hair growth, and skin rejuvenation. PRP-derived exosomes show promise in wound healing, enhancing wound contraction and angiogenesis in diabetic models, but there is limited evidence for their effectiveness in hair growth and skin rejuvenation. The review highlights the need for further research to standardize exosome isolation and delivery methods, with innovative approaches like hydrogel-based preparations being explored. Despite their potential, PRP-derived exosomes are not yet approved by regulatory bodies, necessitating more studies to confirm their clinical efficacy and safety.