TLDR Extracellular vesicles show potential in dermatology, but more research is needed for validation.
This systematic review evaluated the role of extracellular vesicles (EVs) in dermatology, focusing on their therapeutic, diagnostic, and prognostic potential. The review included 52 studies with data from 3066 patients, highlighting some therapeutic efficacy of EVs in dermatologic conditions. However, methodologic inconsistencies and low patient numbers reduced the certainty of these findings. While EVs are being used in cosmeceuticals, no EV-based therapeutics have been approved in dermatology. The review emphasizes the need for future randomized, double-blind, placebo-controlled clinical trials to validate diagnostic and therapeutic claims and support regulatory approvals.
A woman regrew her hair after receiving injections of special cell-derived vesicles.
148 citations
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August 2022 in “Stem Cell Research & Therapy” Encapsulated stem cell exosomes in hydrogel improve wound healing.
8 citations
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June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
3 citations
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May 2022 in “Dermatologic surgery” Exosomes could help with skin and hair, but more research and better methods are needed.
10 citations
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February 2022 in “Journal of cosmetic dermatology” Exosomes from fat-derived stem cells may help regrow hair.
January 2022 in “Aesthetic surgery journal” Extracellular vesicles may effectively treat hair loss with minimal side effects.
44 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” MSC-derived exosomes may help in skin repair and regeneration.
47 citations
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February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
January 2025 in “Cosmetics” Exosomes could improve skin care, but more research is needed to confirm their safety and effectiveness.
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Most emerging dermatological treatments lack strong evidence and require more research.
Exosomes show promise for skin treatments but need more research and regulation in India.
December 2024 in “Molecules” Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.
December 2025 in “Pharmaceutics” Personalized skin rejuvenation using genomics shows promise but needs more research.
