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    GlossaryTreatment Efficacy (Therapeutic Efficacy)

    ability of a treatment to produce desired results in trials

    Treatment Efficacy refers to the ability of a medical treatment or intervention to produce the desired beneficial effect under ideal and controlled conditions, such as in clinical trials. It is a measure of how well a treatment works in a controlled environment, which is different from "effectiveness," which measures how well it works in real-world settings.

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      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community GT20029 - Promising phase II results

      in Research/Science  16 upvotes 6 months ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  25 upvotes 1 year ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.