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In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.

This study found that topical minoxidil 5% foam was effective in promoting hair growth in both the frontal and vertex scalp for men with androgenetic alopecia.

This study reports that PDRN, commonly used for wound healing, may also have anti-melanogenesis and potential skin whitening effects in both experimental models and clinical settings.

This study found that manipulating AKR1D1 expression in human liver cells effectively regulates glucocorticoid clearance and receptor activation, highlighting its role in liver-specific steroid hormone regulation.

This study found that platelet-rich plasma may influence the proliferation of human hair dermal papilla cells by affecting gene expression related to the cell cycle.

This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.

This study found that exosomes from hair follicle mesenchymal stem cells overexpressing lncRNA H19 promoted diabetic skin wound healing by enhancing cell proliferation, migration, and reducing pyroptosis.

This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.

This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.

This study identified aging-related epigenetic and transcriptomic biomarkers and suggested that curcumin might target and inhibit the JUN gene, implicating potential therapeutic strategies against aging.

This study observed that 5% minoxidil topical foam alters gene expression and signaling pathways in the scalp, providing insights into its mechanism of action in men with androgenetic alopecia.

This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.

In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.

This study investigated the formation of Type III brush hair in Chinese Haimen goats and identified genetic factors that may involve heat stress in the process.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.

In this study, whole-genome sequencing of Lanping black-boned sheep identified ERBB4 and ROR1 genes as potentially important in their distinctive hyperpigmentation, enhancing understanding of their genetic evolution from Lanping normal sheep.

This study identified 21 novel circular RNAs in cashmere goats, with nine significantly more expressed during the anagen phase of hair follicle growth, suggesting roles in hair regeneration and cashmere yield enhancement.

This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.

This study suggests that STAT3 signaling in keratinocytes is crucial for maintaining skin homeostasis by regulating hair follicle-specific keratin genes, potentially impacting dermatitis development through microbe-triggered inflammatory responses.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.

This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.

This study presents a detailed overview of lymphatic vessel development and highlights the role of abnormal lymphangiogenesis in various diseases, suggesting that targeting lymphangiogenic factors may improve treatment strategies.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.

This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.