Distinct Mechanisms for Sebaceous Gland Self-Renewal and Regeneration Provide Durability in Response to Injury

May 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

Natalia A. Veniaminova, Yunlong Jia, Adrien M Hartigan, Thomas J Huyge, Shih-Ying Tsai, Marina Grachtchouk, Satoko Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

sebaceous glands stem cell pools PPARγ Krt5 skin injury SG progenitors wound healing hair follicle hair follicle bulge stem cells FGFR signaling stem cell plasticity PPAR gamma keratin 5 fibroblast growth factor receptor

Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

Studysummary This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

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