Transcriptomic Inspection Revealed a Possible Pathway Regulating the Formation of the High-Quality Brush Hair in Chinese Haimen Goat (Capra Hircus)
January 2018
in “
Royal Society Open Science
”
transcriptomic RNAseq differentially expressed genes DEGs protein processing in the endoplasmic reticulum MAPK signaling complement and coagulation cascades heat stress hair growth Type III brush hair RNA sequencing genes ER protein processing MAPK pathway complement system coagulation system Type III hair
TLDR Scientists found genes linked to the growth of high-quality brush hair in Chinese Haimen goats.
In 2018, researchers conducted a study to understand the genetic basis for the formation of high-quality Type III brush hair in Chinese Haimen goats. They utilized transcriptomic RNAseq technology to compare the differentially expressed genes (DEGs) between skin samples from goats with Type III hair and those without it. The study identified 295 DEGs that were significantly enriched in three key KEGG pathways: protein processing in the endoplasmic reticulum, MAPK signaling, and complement and coagulation cascades. These pathways suggested that heat stress might trigger the development of Type III brush hair. The research provided new insights into the genetic factors influencing hair growth and the specific hair characteristics of Haimen goats.
