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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community How does hair loss and recovery work?

      in Chat  12 upvotes 1 year ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.
      Can I still save my hairline at age of 15?

      community Can I still save my hairline at age of 15?

      in General  471 upvotes 1 week ago
      A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

      community Switching from finasteride to dutasteride.

      in Chat 2 years ago
      Switching from finasteride to dutasteride as a treatment for hair loss, with advice given that titrating up to daily use is optimal and results may be seen after one year. Additionally, the user mentioned adding topical minoxidil 5% which has produced good results.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.