1 citations
,
July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that ablative fractional laser treatment significantly alters gene expression related to skin rejuvenation, enhancing wound healing and tissue regeneration processes, and suggests multiple treatments may maximize these effects.
24 citations
,
January 2016 in “Lasers in Medical Science” This study found that non-ablative fractional erbium glass laser treatment affected gene regulation in human skin models by downregulating MMP and interleukin expression, suggesting potential roles in dermal remodeling and anti-inflammatory effects.
July 2024 in “Journal of Investigative Dermatology” Combining certain treatments, including FOL005, may improve healing of difficult wounds.
21 citations
,
July 2024 in “Journal of Investigative Dermatology” This study used single-cell RNA-sequencing data from mouse skin to reveal that fibroblasts show high transcriptional plasticity during wound healing, forming transient microniches early on and stratifying scar tissue into distinct molecular layers over time.
April 2019 in “Journal of Investigative Dermatology” This study in mice found that fractional photothermolysis can improve dermal scar formation by promoting slow, organized collagen regeneration with minimal myofibroblast activation.