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    Glossary CXCR7

    protein receptor involved in cell signaling and hair follicle regulation

    CXCR7, also known as C-X-C chemokine receptor type 7, is a protein that functions as a receptor for certain signaling molecules called chemokines. It plays a role in various biological processes, including cell migration, immune response, and tissue repair. In the context of hair biology, CXCR7 has been implicated in the regulation of hair follicle cycling and may influence conditions like alopecia.

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    Research 30 of 699

    1. Preconditioning with far-infrared irradiation enhances proliferation, cell survival, and migration of rat bone marrow-derived stem cells via CXCR4-ERK pathways Scientific Reports · 2017 · 44 citations
    2. Plerixafor Engages β-Arrestin-Dependent CXCR4 Signaling to Promote Melanogenesis via β-Catenin-MITF Activation Current Issues in Molecular Biology · 2026
    3. Plerixafor Biases CXCR4 Signaling Through β-Arrestin to Promote Melanogenesis via β-Catenin–MITF Activation Preprints.org · 2026
    4. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
    5. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    6. Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis Cancer Research · 2008 · 70 citations
    7. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    8. Author response: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis 2019 · 1 citations
    9. Regulatory T cells in skin utilize the Cxcr4-Cxcl12 axis to promote hair follicle regeneration Cell Reports · 2025
    10. Decision letter: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis 2019
    11. 744 Role of Sdf1-Cxcr4 signaling in mouse appendage regeneration Journal of Investigative Dermatology · 2016
    12. Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia Frontiers in Immunology · 2026
    13. Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin Stem Cells · 2013 · 43 citations
    14. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    15. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    16. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    17. Type 1 interferon signature in the scalp lesions of alopecia areata British Journal of Dermatology · 2010 · 52 citations
    18. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    19. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    20. Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata Annals of Dermatology · 2019 · 17 citations
    21. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    22. Alopecia areata possibly induced by autoimmune reaction in a patient with human T‐cell lymphotropic virus‐1‐associated myelopathy The Journal of Dermatology · 2013 · 6 citations
    23. Skin Wound Healing Elsevier eBooks · 2016 · 5 citations
    24. Granulocyte colony stimulating factor promotes scarless tissue regeneration Cell Reports · 2024 · 4 citations
    25. Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata Journal of Clinical & Cellular Immunology · 2016 · 3 citations
    26. Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss Nature Communications · 2026
    27. Responses of hair follicle gene expression to the cold season and growth promotion technology in Angus and Brahman cattle Domestic Animal Endocrinology · 2026
    28. The polygenic architecture of hidradenitis suppurativa reveals signaling mechanisms that implicate epithelial remodeling 2025
    29. 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics Journal of Investigative Dermatology · 2025
    30. Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2025