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    Glossary Plerixafor

    medication mobilizes stem cells from bone marrow to bloodstream

    Plerixafor, also known as AMD3100, is a medication used to mobilize hematopoietic stem cells from the bone marrow into the bloodstream, making it easier to collect them for transplantation. It works by inhibiting the CXCR4 receptor, which normally helps keep these stem cells in the bone marrow.

    Research 4 of 18

    1. Plerixafor Engages β-Arrestin-Dependent CXCR4 Signaling to Promote Melanogenesis via β-Catenin-MITF Activation Current Issues in Molecular Biology · 2026
    2. Plerixafor Biases CXCR4 Signaling Through β-Arrestin to Promote Melanogenesis via β-Catenin–MITF Activation Preprints.org · 2026
    3. Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration after Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus Journal of Investigative Dermatology · 2014 · 49 citations
    4. 639-P: Pharmacological Mobilization and Recruitment of Bone Marrow Stem Cells Accelerates Diabetic Wound Healing in Rats with Diabetic Complications Diabetes · 2019
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