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GlossaryPlerixafor

medication mobilizes stem cells from bone marrow to bloodstream

Plerixafor, also known as AMD3100, is a medication used to mobilize hematopoietic stem cells from the bone marrow into the bloodstream, making it easier to collect them for transplantation. It works by inhibiting the CXCR4 receptor, which normally helps keep these stem cells in the bone marrow.

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Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

research Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

49 citations, March 2014 in “Journal of Investigative Dermatology”

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

Pharmacological Mobilization and Recruitment of Bone Marrow Stem Cells Accelerates Diabetic Wound Healing in Rats with Diabetic Complications

research Pharmacological Mobilization and Recruitment of Bone Marrow Stem Cells Accelerates Diabetic Wound Healing in Rats with Diabetic Complications

June 2019 in “Diabetes”

Using a combination of AMD3100 and FK506 can speed up and improve wound healing in diabetic rats.

research The Pharmacology of Regenerative Medicine

47 citations, July 2013 in “Pharmacological Reviews”

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

research Oxygen, Metabolism, and Regeneration: Lessons from Mice

35 citations, October 2017 in “Trends in Molecular Medicine”

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

research Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of the ERK 1/2 Signaling Pathways

26 citations, April 2019 in “Advances in wound care”

Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.

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