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    Glossary Plerixafor

    medication mobilizes stem cells from bone marrow to bloodstream

    Plerixafor, also known as AMD3100, is a medication used to mobilize hematopoietic stem cells from the bone marrow into the bloodstream, making it easier to collect them for transplantation. It works by inhibiting the CXCR4 receptor, which normally helps keep these stem cells in the bone marrow.

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    Research 18

    1. Plerixafor Engages β-Arrestin-Dependent CXCR4 Signaling to Promote Melanogenesis via β-Catenin-MITF Activation Current Issues in Molecular Biology · 2026
    2. Plerixafor Biases CXCR4 Signaling Through β-Arrestin to Promote Melanogenesis via β-Catenin–MITF Activation Preprints.org · 2026
    3. Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration after Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus Journal of Investigative Dermatology · 2014 · 49 citations
    4. 639-P: Pharmacological Mobilization and Recruitment of Bone Marrow Stem Cells Accelerates Diabetic Wound Healing in Rats with Diabetic Complications Diabetes · 2019
    5. Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of the <i>ERK 1/2</i> Signaling Pathways Advances in wound care · 2019 · 26 citations
    6. Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives Stem Cells International · 2019 · 17 citations
    7. Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats Diabetes · 2020 · 16 citations
    8. ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts Human Gene Therapy · 2015 · 2 citations
    9. Radioprotection of Lung Tissue by Soy Isoflavones Journal of thoracic oncology · 2013 · 25 citations
    10. Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles Molecular Therapy — Nucleic Acids · 2023 · 18 citations
    11. Pharmacological Mobilization of Endogenous Bone Marrow Stem Cells Promotes Liver Regeneration after Extensive Liver Resection in Rats Scientific Reports · 2018 · 12 citations
    12. Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review International Journal of Molecular Sciences · 2022 · 10 citations
    13. Enhancing diabetic wound healing: advances in electrospun scaffolds from pathogenesis to therapeutic applications Frontiers in bioengineering and biotechnology · 2024 · 5 citations
    14. Pharmacological Strategies for Mitigating Cytarabine-Induced Multi-Organ Toxicity: A Scoping Review on Mechanisms, Efficacy and Clinical Implications Cancers · 2026
    15. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
    16. AAPS and PSRC 2016 Abstract Supplement Plastic and reconstructive surgery. Global open · 2016
    17. Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game? Experimental dermatology · 2012 · 11 citations
    18. Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis Pharmaceutics · 2021 · 15 citations