Transcriptomic Analyses of Regenerating Adult Feathers in Chicken

    October 2015 in “ BMC Genomics
    Chen Siang Ng, Chih-Kuan Chen, Wen‐Lang Fan, Ping Wu, Siao-Man Wu, Jiun‐Jie Chen, Yu-Ting Lai, Chi-Tang Mao, Mei‐Yeh Jade Lu, Di‐Rong Chen, Ze‐Shiang Lin, Kai-Jung Yang, Yuan-An Sha, Tsung-Che Tu, Chih‐Feng Chen, Cheng‐Ming Chuong, Wen‐Hsiung Li
    TLDR Chicken feather growth involves specific genes and shares similarities with hair development.
    The study on regenerating adult chicken feathers used transcriptomic analyses to explore the genetic basis of feather diversity and development. It identified morphotype-specific gene expression patterns and candidate genes involved in growth and differentiation, highlighting the roles of semaphorin signaling and BMP2 in feather morphogenesis. The research found significant up-regulation of genes related to protein synthesis in the pennaceous portion of feathers and those involved in melanin biosynthesis in flight feathers. It also noted similarities between feather and hair follicle development, suggesting shared molecular mechanisms. The study provided a comprehensive dataset for future research on avian feather development and evolution.
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