Wedelolactone, A Natural Coumestan With Multiple Pharmacological Effects

January 2026 in “ Frontiers in Pharmacology ”

Shanshan Han, Minghe Li, Longfei Yang, Xinming Zhuang

Studysummary This review highlights the potential of wedelolactone from the plant Wedelia Chinensis, summarizing its reported pharmacological effects, including anti-inflammatory, antiviral, antibacterial, antitumor, anti-osteoporosis activities, and organ protection based on existing in vitro and in vivo research findings.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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research The Potential Role of Herbal Extract Wedelolactone for Treating Particle-Induced Osteolysis: An In Vivo Study

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research Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway

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research Wedelolactone, A Medicinal Plant-Derived Coumestan, Induces Caspase-Dependent Apoptosis In Prostate Cancer Cells Via Downregulation Of PKCε Without Inhibiting Akt

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research Hair Growth Promoting Activity of Eclipta Alba in Male Albino Rats

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