Assessment of the Chemical Profile and Potential Medical Effects of a Flavonoid-Rich Extract of Eclipta Prostrata L. Collected in the Central Highlands of Vietnam

    October 2023 in “ Pharmaceuticals ”
    Thi Kim Phung Phan, San‐Lang Wang, Nguyễn Quang Vịnh … Mạnh Dũng Đoàn
    Studysummary This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
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    Research cited in this study 10

    1. Eclipta Prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities Biomolecules · 2021
    2. Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta Prostrata and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities Natural Product Sciences · 2020
    3. A Review on Traditional Uses, Phytochemistry, and Pharmacology of Eclipta Prostrata (L.) L. Journal of Ethnopharmacology · 2019
    4. A Brief Overview of Medicinal Activity and Pharmacological Profile of Eclipta Prostrata: A Review International Journal of ChemTech Research · 2019
    5. Phytochemical Analysis of Eclipta Prostrata L. Leaves International Journal of Current Microbiology and Applied Sciences · 2018
    6. Alcoholic Extract of Eclipta Alba Shows In Vitro Antioxidant and Anticancer Activity Without Exhibiting Toxicological Effects Oxidative Medicine and Cellular Longevity · 2017
    7. Potent Antioxidative And UVB Protective Effect Of Water Extract Of Eclipta Prostrata L. The Scientific World JOURNAL · 2014
    8. Wedelolactone, A Medicinal Plant-Derived Coumestan, Induces Caspase-Dependent Apoptosis In Prostate Cancer Cells Via Downregulation Of PKCε Without Inhibiting Akt International Journal of Oncology · 2012
    9. Optimization of Ultrasonic-Assisted Extraction of Total Saponins from Eclipta Prostrasta L. Using Response Surface Methodology Journal of Food Science · 2012
    10. Eclipta Alba Extract With Potential For Hair Growth Promoting Activity Journal of Ethnopharmacology · 2009