Alcoholic Extract of Eclipta Alba Shows In Vitro Antioxidant and Anticancer Activity Without Exhibiting Toxicological Effects

The study investigated the alcoholic extract of Eclipta alba (AEEA) for its antioxidant and anticancer properties, particularly against breast cancer, and evaluated its safety profile. AEEA demonstrated significant in vitro antioxidant activity and induced apoptosis in breast cancer cell lines, inhibiting cell migration without significant cytotoxicity. Toxicological assessments on CF rats showed no adverse effects at doses up to 2000 mg/kg, indicating that AEEA was non-toxic. The findings suggested that AEEA had potential as a safe, natural therapeutic option for cancer treatment, especially in resource-limited settings.