Alcoholic Extract of Eclipta Alba Shows In Vitro Antioxidant and Anticancer Activity Without Exhibiting Toxicological Effects

The study investigated the alcoholic extract of Eclipta alba (AEEA) for its antioxidant and anticancer properties. It was found that AEEA exhibited significant cytotoxic effects on various cancer cell lines, particularly inducing apoptosis in human breast cancer cell lines by disrupting mitochondrial membrane potential and causing DNA damage. Additionally, AEEA inhibited cell migration in MCF 7 and MDA-MB-231 cells in a dose-dependent manner. The extract also demonstrated strong in vitro antioxidant activity, attributed to its high phenolic and flavonoid content. These findings suggested that Eclipta alba had significant potential in complementary and alternative medicine for cancer treatment without exhibiting toxicological effects.