Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway

    March 2019 in “ Frontiers in Pharmacology ”
    Jinyu Yang, Lijun Tao, Bei Liu … Renshi Li
    Studysummary This study found that wedelolactone from Eclipta prostrata L. significantly reduced lung inflammation and fibrosis in mice with bleomycin-induced pulmonary fibrosis, suggesting potential therapeutic benefits through AMPK activation.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Ethnopharmacological Significance of Eclipta Alba (L.) Hassk. (Asteraceae) International Scholarly Research Notices · 2014
    2. Wedelolactone, A Medicinal Plant-Derived Coumestan, Induces Caspase-Dependent Apoptosis In Prostate Cancer Cells Via Downregulation Of PKCε Without Inhibiting Akt International Journal of Oncology · 2012
    3. Hair Growth Promoting Activity of Eclipta Alba in Male Albino Rats Archives of Dermatological Research · 2008