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GlossaryBone Morphogenetic Protein 2 (BMP2)

protein crucial for bone and cartilage development

Bone Morphogenetic Protein 2 (BMP2) is a protein that plays a crucial role in the development of bone and cartilage. It is part of the transforming growth factor-beta (TGF-β) superfamily and is essential for the formation of new bone tissue, making it important in both embryonic development and the healing of bone fractures.

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research BMP2 And BMP7 Play Antagonistic Roles In Feather Induction

88 citations , August 2008 in “Development”

BMP2 and BMP7 have opposite roles in feather formation.

research The Periosteal Requirement and Temporal Dynamics of BMP2-Induced Middle Phalanx Regeneration in the Adult Mouse

31 citations , June 2017 in “Regeneration”

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

research BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy

24 citations , September 2019 in “Experimental cell research”

BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.

research Expression Characteristics of BMP2, BMPR-IA, and Noggin in Different Stages of Hair Follicle in Yak Skin

19 citations , November 2017 in “General and comparative endocrinology”

BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.

research Androgens Downregulate BMP2, Impairing the Inductive Role of Dermal Papilla Cells on Hair Follicle Stem Cells Differentiation

6 citations , November 2020 in “Molecular and Cellular Endocrinology”

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.