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GlossaryBone Morphogenetic Protein 2 (BMP2)

protein crucial for bone and cartilage development

Bone Morphogenetic Protein 2 (BMP2) is a protein that plays a crucial role in the development of bone and cartilage. It is part of the transforming growth factor-beta (TGF-β) superfamily and is essential for the formation of new bone tissue, making it important in both embryonic development and the healing of bone fractures.

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research BMP2 And BMP7 Play Antagonistic Roles In Feather Induction

88 citations, August 2008 in “Development”

BMP2 and BMP7 have opposite roles in feather formation.

research The Periosteal Requirement and Temporal Dynamics of BMP2-Induced Middle Phalanx Regeneration in the Adult Mouse

31 citations, June 2017 in “Regeneration”

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

research BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy

24 citations, September 2019 in “Experimental cell research”

BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.

research Expression Characteristics of BMP2, BMPR-IA, and Noggin in Different Stages of Hair Follicle in Yak Skin

19 citations, November 2017 in “General and comparative endocrinology”

BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.

research Androgens Downregulate BMP2, Impairing the Inductive Role of Dermal Papilla Cells on Hair Follicle Stem Cells Differentiation

6 citations, November 2020 in “Molecular and Cellular Endocrinology”

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.