BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy

September 2019 in “ Experimental cell research ”

Bingjie Cai, Yunpeng Zheng, Jiadi Yan, Junmin Wang, Xiaojun Liu, Guangwen Yin

BMP2 PTEN hair follicle stem cells autophagy epidermal markers adipogenic markers keratinocyte-specific markers wound contraction epidermal regeneration bone morphogenetic protein 2 phosphatase and tensin homolog HFSCs skin repair

Studysummary This study found that BMP2 increased PTEN expression and induced autophagy, promoting hair follicle stem cell differentiation in both in vitro models and a mouse wound model.

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