Genomic Organization, Transcriptomic Analysis, and Functional Characterization of Avian Alpha- and Beta-Keratins in Diverse Feather Forms

    August 2014 in “ Genome Biology and Evolution ”
    Chen Siang Ng, Ping Wu, Wen‐Lang Fan … Wen‐Hsiung Li
    Studysummary This study found that the differential expression of α- and β-keratin genes in feathers may explain their morphological and structural diversity, highlighting the chicken as a model for studying keratin-related diseases.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on academic.oup.com →
    Discuss this study in the Community →

    Research cited in this study 8

    1. The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia Current opinion in cell biology · 2012
    2. The Chicken Frizzle Feather Is Due to an Alpha-Keratin (KRT75) Mutation That Causes a Defective Rachis PLoS Genetics · 2012
    3. Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine Physiology · 2012
    4. Keratin Gene Mutations in Disorders of Human Skin and Its Appendages Archives of Biochemistry and Biophysics · 2010
    5. Evolution of Hard Proteins in the Sauropsid Integument in Relation to the Cornification of Skin Derivatives in Amniotes Journal of anatomy · 2009
    6. Molecular Evolution of the Keratin Associated Protein Gene Family in Mammals: Role in the Evolution of Mammalian Hair BMC Evolutionary Biology · 2008
    7. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    8. Terrestrial Vertebrates Have Two Keratin Gene Clusters; Striking Differences in Teleost Fish European Journal of Cell Biology · 2005

    Related research 2

    1. Keratin Intermediate Filaments in the Colon: Guardians of Epithelial Homeostasis International journal of biochemistry & cell biology · 2020
    2. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989